Strain Pattern on Electrocardiogram Is Associated with Increased Carotid Intima-Media Thickness in Patients with Aortic Valve Stenosis
| Autor: | Meliza Goi Roscani, João Carlos Hueb, Liciana Vaz de Arruda Silveira, Silméia Garcia Zanati, Juliana da Cunha Duarte, Daniele Andreza Antonelli Rossi, Gustavo Nicolodi Augusto, Jonas A. Araújo, Juliana Irani Fratucci De Gobbi, Taina Fabri Carneiro Valadão, Regina C. Coneglian, Beatriz Bojikian Matsubara |
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| Přispěvatelé: | Universidade Federal de São Carlos (UFSCar), Universidade Estadual Paulista (Unesp) |
| Rok vydání: | 2016 |
| Předmět: |
Carotid Artery Diseases
Male medicine.medical_specialty 030204 cardiovascular system & hematology Carotid Intima-Media Thickness Severity of Illness Index Ventricular Function Left Coronary artery disease Electrocardiography 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine Odds Ratio medicine Humans Prospective Studies cardiovascular diseases 030212 general & internal medicine Pathological Aged Subclinical infection Aged 80 and over Chi-Square Distribution business.industry Carotid ultrasonography Signal Processing Computer-Assisted Aortic Valve Stenosis General Medicine Odds ratio Middle Aged medicine.disease Plaque Atherosclerotic Stenosis Carotid Arteries Logistic Models Intima-media thickness Aortic valve stenosis Asymptomatic Diseases Multivariate Analysis cardiovascular system Cardiology Female Surgery Stress Mechanical Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 0890-5096 |
| DOI: | 10.1016/j.avsg.2016.01.047 |
| Popis: | Made available in DSpace on 2018-12-11T17:04:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-08-01 Background Coronary artery disease is present in at least 30% of patients with degenerative aortic stenosis (AS). Atherosclerosis also performs an important role in the progression of AS, because of the similarities of pathological mechanisms in both conditions. The electrocardiogram (EKG) strain pattern is associated with structural myocardial change and subendocardial ischemia and has been worldwide used as a marker of AS severity. We hypothesized that EKG strain pattern would be a marker of atherosclerosis as well in AS patients. The aim of this study was to associate the presence of EKG strain pattern in AS patients with the carotid intima-media thickness (CIMT). Methods Fifty-two consecutive patients referred from the cardiology clinic with moderate or severe AS were included in the study and underwent clinical evaluation, EKG, transthoracic echocardiography, and carotid ultrasonography, following statistical analysis of the results. Results There was a significant association between left ventricular EKG strain and increased CIMT (P = 0.001). The presence of strain increased the odds of abnormal CIMT (P = 0.004, odds ratio 9.7, 95% confidence interval 2.4–45.0), in a model adjusted for age and clinical diagnosis of systemic arterial hypertension. Additionally, EKG strain was associated with the presence of atherosclerotic plaque in at least one carotid artery (P = 0.011). Conclusion Our results suggest that AS patients with EKG strain pattern should be further investigated for the diagnosis of subclinical atherosclerotic disease. Medicine Department Cardiology Division São Carlos Federal University –UFSCar Botucatu Medical School Medicine Department Universidade Estadual Paulista – UNESP Biosciences Institute of Botucatu Physiology Department Universidade Estadual Paulista – UNESP Biosciences Institute of Botucatu Statistical Department Universidade Estadual Paulista – UNESP Internal Medicine Department Cardiology Division Botucatu Medical School Universidade Estadual Paulista – UNESP Botucatu Medical School Medicine Department Universidade Estadual Paulista – UNESP Biosciences Institute of Botucatu Physiology Department Universidade Estadual Paulista – UNESP Biosciences Institute of Botucatu Statistical Department Universidade Estadual Paulista – UNESP Internal Medicine Department Cardiology Division Botucatu Medical School Universidade Estadual Paulista – UNESP |
| Databáze: | OpenAIRE |
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