Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects
| Autor: | Luciano Antonaci, Raffaele Di Marzo, Teresa Paolucci, Fiammetta Troili, Anna Rosa Catizzone, U. Massafra, Manuela Giardini, Enrica Maggiori, Costanza Guglielmo, Alessandro Bomprezzi, Bartolomeo Violo, Chiara Giorgio, Anna Cuguttu, Paola Emilia Ferrara, Gianpaolo Ronconi, Domenico Russo, Dario Dorato, Renato Vellucci, Flora Canzona, Massimo Mammucari, Piergiovanni Rocchi, Alessandra Gallo, Fabio Gori, Stefano Brauneis, Stefania Santini, Barbara Bifarini, Domenico Rocco Mediati, Massimo di Carlo, Silvia Natoli, Alberto Migliore |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Drug
Technology medicine.medical_specialty Injections Intradermal Mesotherapy Skin Absorption Science media_common.quotation_subject Pain Review Article General Biochemistry Genetics and Molecular Biology Scientific evidence law.invention 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Informed consent law medicine Animals Humans Intensive care medicine General Environmental Science media_common Analgesics Modalities business.industry Localized pain Dermis General Medicine Treatment Outcome Italy Settore MED/41 Practice Guidelines as Topic Medicine Position paper business 030217 neurology & neurosurgery Forecasting |
| Zdroj: | The Scientific World Journal, Vol 2020 (2020) The Scientific World Journal |
| Popis: | Intradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug’s kinetics, slowing absorption and prolonging the local mechanism of action. It is successfully applied in the treatment of some forms of localized pain syndromes and other local clinical conditions. It could be suggested when a systemic drug-sparing effect is useful, when other therapies have failed (or cannot be used), and when it can synergize with other pharmacological or nonpharmacological therapies. Despite the lack of randomized clinical trials in some fields of application, a general consensus is also reached in nonpharmacological mechanism of action, the technique execution modalities, the scientific rationale to apply it in some indications, and the usefulness of the informed consent. The Italian Mesotherapy Society proposes this position paper to apply intradermal therapy based on scientific evidence and no longer on personal bias. |
| Databáze: | OpenAIRE |
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