Acute leukemic appendicitis in a patient with acute promyelocytic leukemia

Autor: Ajeet Gajra, Subhraleena Das, Srivalli Gopaluni, Hatim Karachiwala
Rok vydání: 2012
Předmět:
Zdroj: Journal of Cancer Research and Therapeutics, Vol 8, Iss 1, Pp 132-134 (2012)
ISSN: 0973-1482
DOI: 10.4103/0973-1482.95194
Popis: Leukemic and lymphomatous infiltration of the appendix is a rare complication. We present the case of a 31-year-old male with acute promyelocytic leukemia who developed acute abdomen on day 11 of induction chemotherapy with idarubicin and cytarabine. After appropriate work-up, a clinical diagnosis of acute appendicitis was made. Despite severe pancytopenia, he successfully underwent laparoscopic appendectomy. The final pathology revealed leukemic infiltration of the appendix. It is hypothesized that the leukemic infiltration may play a role in the development of acute appendicitis. Further, this case demonstrates the need to maintain a high index of suspicion and prompt surgical intervention for surgical pathologies in neutropenic patients.
Databáze: OpenAIRE