Contralateral sinus involvement of surgically treated unilateral allergic fungal rhinosinusitis
| Autor: | Talal A. Alandejani, Abdulaziz AlQahtani, Ali S. Alqahtani, A. Alzarei, H. Mokarbesh, Osama A. Marglani, N. Alshaikh, Saad Alsaleh, Farhan Alshammari, Mohammad Aloulah, Abdulwahab Alamri, A. Musleh, Fahad Alfawwaz |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Budesonide medicine.medical_specialty Rhinitis Allergic Perennial Disease 03 medical and health sciences 0302 clinical medicine Recurrence Statistical significance Paranasal Sinuses Humans Medicine Sinusitis Therapeutic Irrigation 030223 otorhinolaryngology Glucocorticoids Sinus (anatomy) Retrospective Studies business.industry General Medicine Perioperative Surgery medicine.anatomical_structure Mycoses Otorhinolaryngology Case-Control Studies 030220 oncology & carcinogenesis Radiological weapon Female Neurosurgery business medicine.drug |
| Zdroj: | European Archives of Oto-Rhino-Laryngology. 274:3097-3101 |
| ISSN: | 1434-4726 0937-4477 |
| DOI: | 10.1007/s00405-017-4604-x |
| Popis: | Recurrence of allergic fungal rhinosinusitis (AFRS) is well recognized. However, there is scarcity in the literature describing involvement of the non-diseased sinuses. We aimed to evaluate the recurrence forms of unilateral AFRS as well as to study the possible predictor factors of developing the disease in the contralateral side. Patients with exclusive unilateral AFRS from (2010 to 2015) were enrolled in multi-institutional case-control study. All patients were evaluated after endoscopic sinus surgery for recurrence. Patient's records were reviewed for demographics, medical treatment, and clinical, radiological, and surgical data. A total of 68 patients were identified. Delayed contralateral involvement after the initial surgery was found in 30.8% with mean duration of recurrence 16.9 months. A significant association was found with the presence of pre-operative contralateral symptoms and signs of inflammation (OR 3.49, 95% CI 1.19-10.22, p value 0.02). Post-operative use of budesonide irrigation was associated with less contralateral involvement (OR 0.11, 95% CI 0.01-0.87, p value 0.01). Association of other variables like: comorbidities, perioperative use of systemic steroid, radiological signs, extent of surgery, additional surgery to the contralateral side, and post-operative use of systemic steroids did not show statistical significance. Involvement of the contralateral sinuses in 30% of unilateral AFRS cases is considered significant. The non-diseased sinuses should be involved in the routine endoscopic examination and post-operative treatment. Further studies are necessary to investigate the possibility of prophylactic surgical intervention of the non-diseased sinuses. |
| Databáze: | OpenAIRE |
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