Pulmonary blood volume measured by contrast enhanced ultrasound : a comparison with transpulmonary thermodilution
| Autor: | M. A. Soliman Hamad, R.A. Bouwman, Hendrikus H. M. Korsten, H.C. van Assen, Massimo Mischi, Ingeborg H F Herold |
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| Přispěvatelé: | Medical signal processing, Signal Processing Systems, Biomedical Diagnostics Lab, Eindhoven MedTech Innovation Center |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
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medicine.medical_specialty medicine.medical_treatment Thermodilution Sulfur Hexafluoride Hemodynamics Contrast Media Blood volume Intensive care Internal medicine medicine Humans Bland–Altman plot Saline Lung Phospholipids Aged Aged 80 and over Blood Volume Blood Volume Determination business.industry Ultrasound Reproducibility of Results Middle Aged Image Enhancement Cardiac surgery Anesthesiology and Pain Medicine Cardiology Female business Echocardiography Transesophageal Contrast-enhanced ultrasound |
| Zdroj: | British Journal of Anaesthesia, 115(1), 53-60. Oxford University Press |
| ISSN: | 0007-0912 |
| Popis: | Background Blood volume quantification is essential for haemodynamic evaluation guiding fluid management in anaesthesia and intensive care practice. Ultrasound contrast agent (UCA)-dilution measured by contrast enhanced ultrasound (CEUS) can provide the UCA mean transit time (MTT) between the right and left heart, enabling the assessment of the intrathoracic blood volume (ITBVUCA). The purpose of the present study was to investigate the agreement between UCA-dilution using CEUS and transpulmonary thermodilution (TPTD) in vitro and in vivo. Methods In an in vitro setup, with variable flows and volumes, we injected a double indicator, ice-cold saline with SonoVue®, and performed volume measurements using transesophageal echo and thermodilution by PiCCO®. In a pilot study, we assigned 17 patients undergoing elective cardiac surgery for pulmonary blood volume (PBV) measurement using TPTD by PiCCO® and ITBV by UCA-dilution. Correlation coefficients and Bland-Altman analysis were performed for all volume measurements. Results In vitro, 73 experimental MTT's were obtained using PiCCO® and UCA-dilution. The volumes by PiCCO® and UCA-dilution correlated with true volumes; rs=0.96 (95% CI, 0.93–0.97; P |
| Databáze: | OpenAIRE |
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