Popis: |
Objectives: To compare indices of vascular stiffness and markers of adiposity and inflammation in “healthy” subjects with/without components of the metabolic syndrome (met-x). Methods: Subjects satisfying ≥1 (≥1 Met-X;) and no criteria (0 Met-X) were recruited (IDF 2006). All were lifelong non-smokers, normotensive, normolipidaemic and normoglycaemic. Augmentation index (AIx) and pulse wave velocity (PWV) were measured using applanation tonometry (Sphygmacor & Vicorder). Fasting leptin, adiponectin, IL-6, TNFα & MCP-1 were measured. Unpaired students t-test and Fischer’s exact test was used to detect differences. Results: Anthropometric, metabolic and haemodynamic indices of the met-x syndrome were significantly higher in the ≥1 Met-X group (p |