Li-gazing at the crest: Modulation of the neural crest by the ubiquitin pathway
| Autor: | Samuela Kabbara, Quenten Schwarz, Rachael Lumb, Sophie Wiszniak, Michaela Scherer |
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| Přispěvatelé: | Wiszniak, Sophie, Lumb, Rachael, Kabbara, Samuela, Scherer, Michaela, Schwarz, Quenten |
| Rok vydání: | 2013 |
| Předmět: |
Cell type
Population ved/biology.organism_classification_rank.species Embryonic Development Biology Biochemistry Neural crest Animals Humans education Model organism Transcription factor education.field_of_study Stem cell Ubiquitin ved/biology Embryogenesis Ubiquitination Gene Expression Regulation Developmental Cell Biology Cell biology Neural Crest Crest Signal Transduction Transcription Factors |
| Zdroj: | The International Journal of Biochemistry & Cell Biology. 45:1087-1091 |
| ISSN: | 1357-2725 |
| DOI: | 10.1016/j.biocel.2013.02.014 |
| Popis: | Neural crest cells are a transient population of stem cells that give rise to a diverse range of cell types during embryonic development. Through gain-of-function and loss-of-function studies in several model organisms many key signalling pathways and cell-type specific transcription factors essential for neural crest cell development have been identified. However, the role of post-translational regulation remains largely unexplored. Here we review this cell type with a foray into the known and potential roles of the ubiquitination pathway in key signalling events during neural crest cell development. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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