Gentamicin-collagen sponge for local applications: 10 cases of chronic osteomyelitis followed for 1 year
| Autor: | Carsten Tørholm, Villiam Damholt, Per Schultz Jørgensen, Tune Ipsen |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty Bovine collagen medicine.drug_class Administration Topical Antibiotics medicine Humans Orthopedics and Sports Medicine Prospective Studies Aged Drug Carriers Wound Healing biology business.industry Aminoglycoside Osteomyelitis Middle Aged equipment and supplies biology.organism_classification medicine.disease Surgery Sponge Chronic osteomyelitis Collagen sponge Female Gentamicin Collagen Gentamicins Osteitis business Follow-Up Studies medicine.drug |
| Zdroj: | Acta Orthopaedica Scandinavica. 62:592-594 |
| ISSN: | 0001-6470 |
| DOI: | 10.3109/17453679108994503 |
| Popis: | A bovine collagen sponge containing gentamicin was applied locally in 10 patients with chronic osteomyelitis who were then followed for 1 year postoperatively. No adverse effects or recurrence of infections was observed. The release of gentamicin from the sponge was more complete and rapid than has been reported with polymethyl methacrylate (PMMA) beads. Compared with previous reports on PMMA beads, a much higher gentamicin concentration in the wound exudate can be expected after implantation of the collagen sponge, which is easy to apply and does not require a second operation for removal. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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