Asymmetric synthesis of (R)-sulcatol
| Autor: | Stephen G. Davies, G. Darren Smyth |
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| Rok vydání: | 1996 |
| Předmět: | |
| Zdroj: | Tetrahedron: Asymmetry. 7:1005-1006 |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/0957-4166(96)00103-6 |
| Popis: | The insect pheromone ( R )-sulcatol, 2-hydroxy-6-methylhept-5-ene, is synthesised via a stereoselective conjugate addition of ( R )-lithium N , α -dimethylbenzylamide to tert -butyl( E , E )-hexa-2,4-dienoate, Grignard addition, and stereospecific Meisenheimer rearrangement. Hydrogenation of the olefin, dehydration of the tertiary alcohol and NO bond cleavage complete the synthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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