Convection-enhanced delivery with controlled catheter movement: A parametric finite element analysis

Autor:	Jason N. Mehta, Manuel K. Rausch, Christopher G. Rylander
Rok vydání:	2022
Předmět:	Catheters Drug Delivery Systems Computational Theory and Mathematics Applied Mathematics Modeling and Simulation Finite Element Analysis Biomedical Engineering Brain Convection Molecular Biology Software
Zdroj:	International journal for numerical methods in biomedical engineering. 38(9)
ISSN:	2040-7947
Popis:	Convection-enhanced delivery (CED) is an investigational method for delivering therapeutics directly to the brain for the treatment of glioblastoma. However, it has not become a common clinical therapy due to an inability of CED treatments to deliver therapeutics in a large enough tissue volume to fully saturate the target region. We have recently shown that the combination of controlled catheter movement and constant pressure infusions can be used to significantly increase volume dispersed (V
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed313db729c10bad72326d84256c4646 https://pubmed.ncbi.nlm.nih.gov/35763587 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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