Changing epidemiology of the respiratory bacteriology of patients with cystic fibrosis–data from the European cystic fibrosis society patient registry
| Autor: | Pavel Drevinek, Halyna Makukh, Muriel Thomas Sciensano, Rita Ujhelyi, Godfrey Fletcher, Vincent Gulmans, Milan Macek, Kris De Boeck, Elise Lammertyn, Hanne Vebert Olesen, Luísa Pereira, Isabelle de Monestrol, Siobhán B. Carr, Rebecca Cosgriff, Simona Mosescu, Anne Farge, Kęstutis Malakauskas, Oxana Turcu, Carlos Vazquez-Cordero, R. Padoan, Nataliya Kashirskaya, Lutz Naehrlich, Andreas Pfleger, Meir Mei-Zahav, S. Fustik, Annalisa Orenti, Zane Timpare, A. Zolin, Milan Rodić, Anders Lindblad, Elpis Hatziagorou, Uros Krivec, Hana Kayserova, Andreas Jung |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine Adult Male medicine.medical_specialty Registry Staphylococcus aureus Cystic Fibrosis Epidemiology Stenotrophomonas maltophilia Cystic fibrosis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Prevalence Infection control Humans Registries Child Respiratory Tract Infections biology business.industry Incidence (epidemiology) Burkholderia cepacia complex Nontuberculous Mycobacteria biology.organism_classification medicine.disease Europe 030104 developmental biology Clinical research 030228 respiratory system Socioeconomic Factors Pediatrics Perinatology and Child Health Epidemiological Monitoring Pseudomonas aeruginosa Nontuberculous mycobacteria Female business |
| Zdroj: | Hatziagorou, E, Orenti, A, Drevinek, P, Kashirskaya, N, Mei-Zahav, M, De Boeck, K & on behalf of the ECFSPR 2020, ' Changing epidemiology of the respiratory bacteriology of patients with cystic fibrosis–data from the European cystic fibrosis society patient registry ', Journal of Cystic Fibrosis, vol. 19, no. 3, pp. 376-383 . https://doi.org/10.1016/j.jcf.2019.08.006 |
| DOI: | 10.1016/j.jcf.2019.08.006 |
| Popis: | Background Monitoring changes in the epidemiology of cystic fibrosis (CF) pathogens is essential for clinical research, quality improvement, and clinical management. Methods We analyzed data reported to the European Cystic Fibrosis Society Patient Registry (ECFSPR) from 2011 to 2016 to determine the overall and the age-specific annual prevalence and incidence of selected CF pathogens and their trends during these years. The ECFSPR collects data on three chronic infections: Pseudomonas aeruginosa (PsA), Burkholderia cepacia complex Species (BCC) and Staphylococcus aureus (SA), as well as on the occurrence of non-tuberculous mycobacteria (NTM) and Stenotrophomonas maltophilia (SM). The same analyses were performed for different country groups, according to their gross national income (GNI). Results The pathogens with the highest prevalence were SA and PsA, with prevalence, in 2016, equal to 38.3% and 29.8% respectively, followed by SM (8.1%). The pathogens with the lowest prevalence were NTM (3.3%) and BCC (3.1%). The overall prevalence and incidence significantly decreased for PsA; they also decreased for BCC, while they increased significantly for SA. The overall prevalence of NTM and SM increased significantly. The most considerable prevalence changes were observed for PsA, which decreased across all income country groups and all age strata (with the exception of 0–1 years) The prevalence and incidence of pathogens differed significantly according to GNI. Conclusions The epidemiology of CF pathogens in Europe has changed; epidemiologic data differ significantly among countries with different socio-economic status. The causes of these observations are multifactorial and include improvements in clinical care and infection control. |
| Databáze: | OpenAIRE |
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