The Evaluation of Thrombospondin 1 Levels in Patients with Acromegaly

Autor:	Ayfer Colak, Merve Zeytinli, Baris Onder Pamuk, Demet Ince, Mustafa Demirpence, Hamiyet Yilmaz
Rok vydání:	2020
Předmět:	medicine.medical_specialty business.industry lcsh:R lcsh:Medicine thrombospondin medicine.disease Gastroenterology colon cancer Internal medicine Acromegaly Thrombospondin 1 medicine acromegaly In patient business
Zdroj:	İstanbul Medical Journal, Vol 21, Iss 1, Pp 13-17 (2020)
ISSN:	2148-094X 2619-9793
Popis:	Introduction:Acromegaly is a rare disease caused by overproduction of growth hormone (GH) secreted from a benign pituitary adenoma. It has been shown in many studies that the incidence of cancer is increased in patients with acromegaly with increased GH and insulin-like growth factor-1 (IGF-1). Especially, colon cancer is more common. Thrombospondin-1 (TSP-1) is a glycoprotein that is thought to play an important role in cancer formation. This study aimed to evaluate circulating TSP-1 levels in patients with acromegaly.Methods:This study was a case-control study. Fifty-two patients with active acromegaly with GH
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2e44465a7e33f0942c00d7e57bcd79 https://doi.org/10.4274/imj.galenos.2019.19794 Zobrazit plný text záznamu Plný text ve formátu PDF