Human immune responses to vaccines in the first year of life: Biological, socio-economic and ethical issues – A viewpoint
| Autor: | Muhammed O. Afolabi, Olubukola T. Idoko, Martin O. C. Ota, Ezra O. Ogundare |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Population Psychological intervention Developing country Immunity Intervention (counseling) medicine Humans Intensive care medicine education Developing Countries Vaccines education.field_of_study General Veterinary General Immunology and Microbiology Immunization Programs business.industry Public health Infant Newborn Public Health Environmental and Occupational Health Infant Infant mortality Child mortality Infectious Diseases Socioeconomic Factors Molecular Medicine Female Public Health business |
| Zdroj: | Vaccine. 31:2483-2488 |
| ISSN: | 0264-410X |
| DOI: | 10.1016/j.vaccine.2012.06.018 |
| Popis: | Human newborns are vulnerable to infectious diseases that account for majority of the morbidity and mortality, particularly in first year of life. Vaccines have become the most effective public health intervention strategy to curtail the prevalence of these infectious diseases. Although vaccines against a number of diseases exist, there are no vaccines against many other diseases that commonly affect children. The adequate assessment of immune responses to vaccines is an important step in the development of vaccines. However, a number of biological and "non-medical" socio-economic and ethical factors could influence either the administration and/or evaluation of vaccines in infants. Recognition and understanding of these determinants are crucial in planning interventions and for logical interpretations of results. |
| Databáze: | OpenAIRE |
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