Collagen concentrations in dissected tissue compartments of rat uterus on days 6, 7 and 8 of pregnancy
Autor: | G. F. Spears, DB Myers, DE Clark, P. R. Hurst |
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Rok vydání: | 1992 |
Předmět: |
Embryology
medicine.medical_specialty Stromal cell Uterus Biology Extracellular matrix Hydroxyproline chemistry.chemical_compound Endocrinology Pregnancy Internal medicine medicine Decidua Animals Embryo Implantation Myometrium Obstetrics and Gynecology Rats Inbred Strains Cell Biology Embryonic Tissue medicine.disease Embryo Mammalian Rats medicine.anatomical_structure Reproductive Medicine chemistry In utero Pregnancy Animal Female Collagen |
Zdroj: | Journal of reproduction and fertility. 94(1) |
ISSN: | 0022-4251 |
Popis: | Implantation and non-implantation sites were dissected into myometrial and stromal components; a decidual/embryonic region was obtained on Days 7 and 8 of pregnancy. The concentration of collagen (as a percentage of the dry weight of tissue), measured by hydroxyproline analysis, was significantly lower in the implantation regions than in the non-implant regions in all areas studied. The concentrations in the antimesometrial myometrium and stroma of the implantation region remained the same over the days studied. In contrast, the mesometrial collagen concentration in the implantation region declined from Day 6 to Day 8 of pregnancy. Collagen concentration was low within the decidual/embryonic tissue on Days 7 and 8 of pregnancy. Remodelling of collagen within the embryonic area appears to be an important feature of the uterine response to implantation in rats. |
Databáze: | OpenAIRE |
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