A novel non-enzymatic ECL sensor for glucose using palladium nanoparticles supported on functional carbon nanotubes
| Autor: | Yaqi Jiang, Tian-tian Jia, Xiaomei Chen, Hai-zhu Liu, Zhi-min Cai, Zhi-jie Lin, Xi Chen |
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| Rok vydání: | 2009 |
| Předmět: |
Biomedical Engineering
Biophysics Analytical chemistry Nanoparticle chemistry.chemical_element Carbon nanotube Biosensing Techniques Electrochemistry Redox law.invention Luminol chemistry.chemical_compound law Electrochemiluminescence Detection limit Chemistry Nanotubes Carbon General Medicine Equipment Design Equipment Failure Analysis Glucose Luminescent Measurements Nanoparticles Palladium Biotechnology Nuclear chemistry |
| Zdroj: | Biosensorsbioelectronics. 24(12) |
| ISSN: | 1873-4235 |
| Popis: | A novel non-enzymatic electrochemiluminescence (ECL) sensor based on palladium nanoparticles (PdNPs)-functional carbon nanotubes (FCNTs) was discovered for glucose detection. PdNPs were homogeneously modified on FCNTs using a facile spontaneous redox reaction method. Their morphologies were characterized by transmission electron microscopy (TEM). Based on ECL experimental results, the PdNPs-FCNTs-Nafion film modified electrode displayed high electrocatalytic activity towards the oxidation of glucose. The free radicals generated by the glucose oxidation reacted with the luminol anion (LH(-)), and enhanced the ECL signal. Under the optimized conditions, the linear response of ECL intensity to glucose concentration was valid in the range from 0.5 to 40 micromol L(-1) (r(2)=0.9974) with a detection limit (S/N=3) of 0.09 micromol L(-1). In addition, the modified electrode presented high resistance towards the poisoning of chloride ion, high selectivity and long-term stability. In order to verify the sensor reliability, it was applied to the determination of glucose in glucose injection samples. The results indicated that the proposed approach provided a highly sensitive, more facile method with good reproducibility for glucose determination, promising the development of a non-enzymatic ECL glucose sensor. |
| Databáze: | OpenAIRE |
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