Minimal residual disease in autologous hematopoietic harvests from breast cancer patients
| Autor: | R H Mertelsmann, Alexandros Spyridonidis, Dirk Behringer, W. Bernhardt, S. Fetscher, Reinhard Henschler |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Neoplasm Residual medicine.medical_treatment Antineoplastic Agents Breast Neoplasms Hematopoietic stem cell transplantation Breast cancer medicine Humans Chemotherapy Dose-Response Relationship Drug business.industry Hematopoietic Stem Cell Transplantation Cancer Hematology medicine.disease Chemotherapy regimen Minimal residual disease Surgery Transplantation Treatment Outcome surgical procedures operative medicine.anatomical_structure Oncology Disease Progression Female Bone marrow business |
| Zdroj: | Annals of Oncology. 9:821-826 |
| ISSN: | 0923-7534 |
| DOI: | 10.1023/a:1008344708061 |
| Popis: | The increasing use of high-dose chemotherapy with autologous hematopoietic transplantation for the treatment of solid malignancies has raised concern about the role of tumor cells contaminating the grafts. Minimal residual disease (MRD) in autologous grafts has became a dynamic and intensively studied field in oncology. This review discusses the current status of MRD in breast cancer autografts and presents existing data on detection methodology, clinical relevance, biologic characteristics and purging techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|