EBUS-TBNA in the Workup of a Mediastinal Mass
| Autor: | Walter De Wever, Jonas Yserbyt, Luc Van Zandweghe, Christophe Dooms |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Pulmonary and Respiratory Medicine medicine.medical_specialty Malignant peripheral nerve sheath tumor Schwannoma Mediastinal Neoplasms Nerve Sheath Neoplasms Fluorodeoxyglucose F18 medicine Humans Endoscopic Ultrasound-Guided Fine Needle Aspiration Peripheral Nerve Sheath medicine.diagnostic_test business.industry medicine.disease Magnetic Resonance Imaging Mediastinal Neoplasm Fine-needle aspiration Positron emission tomography Positron-Emission Tomography Female Radiology Sarcoma Radiopharmaceuticals Nuclear medicine business Nerve sheath neoplasm |
| Zdroj: | Journal of Bronchology & Interventional Pulmonology. 19:162-164 |
| ISSN: | 1944-6586 |
| DOI: | 10.1097/lbr.0b013e318250341e |
| Popis: | Guided by endobronchial ultrasound (EBUS), mediastinal lymph nodes can be reached in a safe, minimally invasive manner, allowing fine needle aspiration for cytologic diagnosis with a high sensitivity and specificity. In describing the following clinical case, we demonstrate the use of EBUS-transbronchial needle aspiration (TBNA) in the workup of a paratracheal mass in a young female patient. Immunocytochemical analysis revealed it to be a peripheral nerve sheath tumor. EBUS-TBNA complemented computerized tomography, fluoro-deoxy-glucose positron emission tomography, and magnetic resonance imaging in establishing the diagnosis of this infrequently encountered mediastinal neoplasm. Fluoro-deoxy-glucose positron emission tomography has a potential to discriminate between high-grade sarcoma and benign soft tissue tumors, but it remains unreliable to differentiate benign schwannoma from low-grade sarcomas such as malignant peripheral nerve sheath tumor. When properly prepared, cell blocks obtained from TBNA of a paratracheal mass offer the possibility of cytologic examination and immunocytochemical staining, confirming the diagnosis of mediastinal neurogenic tumors. |
| Databáze: | OpenAIRE |
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