Percutaneous transhepatic biliary drainage may be the preferred preoperative drainage method in hilar cholangiocarcinoma
| Autor: | Joseph Leung, Wenbo Meng, Ying Liu, Bing Bai, Yongjiang Ba, Kexiang Zhu, Xiaoliang Zhu, Yanyan Lin, Xun Li, Ping Yue, Wenhui Wang, Wence Zhou, Haiping Wang, Lei Zhang |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Biliary drainage Original article Endoscopic retrograde cholangiopancreatography medicine.diagnostic_test business.industry Incidence (epidemiology) Retrospective cohort study medicine.disease Surgery 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Medicine Pancreatitis 030211 gastroenterology & hepatology Pharmacology (medical) In patient lcsh:Diseases of the digestive system. Gastroenterology Percutaneous transhepatic biliary drainage Drainage lcsh:RC799-869 business |
| Zdroj: | Endoscopy International Open Endoscopy International Open, Vol 08, Iss 02, Pp E203-E210 (2020) |
| ISSN: | 2196-9736 2364-3722 |
| Popis: | Background and study aims Preoperative biliary drainage of hilar cholangiocarcinoma (HC) is controversial. The goal of this study was to compare the clinical outcome and associated complications for types II, III, and IV HC managed by percutaneous transhepatic biliary drainage (PTBD) and endoscopic retrograde cholangiopancreatography (ERCP). Patients and methods Between January 2011 and June 2017, a total of 180 patients with II, III, and IV HC were enrolled in this retrospective cohort study. According to the drainage method, patients were divided into two groups: PTBD (n = 81) and ERCP (n = 99). This study was registered with ClinicalTrials.gov, NCT03104582, and was completed. Results Compared with the PTBD group, the ERCP group had a higher incidence of post-procedural cholangitis (37 [37.37 %] vs. 18 [22.22 %], P = 0.028) and pancreatitis (17 [17.17 %] vs. 2 [2.47 %], P = 0.001); required more salvaged biliary drainage (18 [18.18 %] vs. 5 [6.17 %], P = 0.029), and incurred a higher cost (P Conclusion Compared to ERCP, PTBD reduced the rate of cholangitis, pancreatitis, salvage biliary drainage, and decreased hospitalization costs in patients with types II, III, and IV HC. Risk of cholangitis for patients with types III and IV was significantly lower in the PTBD group. |
| Databáze: | OpenAIRE |
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