Clinical Practice Guidelines for Liver Transplantation in Saudi Arabia
| Autor: | Mohammed Saad Alqahtani, Waleed Al-Hamoudi, Abduljaleel Alalwan, Wael A. O’Hali, Faisal Abaalkhail, Hamad Al-Bahili, Mohammed Y Alghamdi, Mohammed Shagrani, Saleh Alabbad, Mohammed Al Sebayel, Nasser Al-Masri, Saleh A. Alqahtani |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Tissue and Organ Procurement business.industry medicine.medical_treatment Mortality rate Saudi Arabia General Medicine Liver transplantation medicine.disease Tissue Donors Organ transplantation Liver Transplantation Transplantation Liver disease Diabetes Mellitus Type 2 Epidemiology medicine Humans Organ donation Steatohepatitis Intensive care medicine business Societies Medical |
| Zdroj: | Saudi Medical Journal. 42:927-968 |
| ISSN: | 1658-3175 0379-5284 |
| Popis: | The demand for liver transplantation in the Kingdom of Saudi Arabia (KSA) is associated with the country's high burden of liver disease. Trends in the epidemiology of liver transplantation indications among recipients in KSA have changed over 20 years. Non-alcoholic steatohepatitis has eclipsed the hepatitis C virus in the country due to the effective treatment strategies for HCV. Risk factors for NASH, like type 2 diabetes mellitus, obesity, and hyperlipidemia, are becoming a major concern and a leading indication for liver transplantation in the KSA. There is also a significantly increased prevalence and incidence of genetic adult familial liver diseases in KSA. New immunosuppressive agents and preservation solutions, improved surgical capabilities, and early disease recognition and management have increased the success rate of liver transplant outcome but concerns about the side effects of immunosuppressive therapy can jeopardise long-term survival outcomes. Despite this, indications for liver transplantation continue to increase, resulting in ongoing challenges to maximize the number of potential donors and reduce patient mortality rate while expecting to get transplanted. The Saudi Center of Organ Transplant is the recognized National Organ Donation Agency for transplantation, which renders important support for procurement and allocation of organs. This guidance document aims to help healthcare providers in managing patients in the liver transplant setting. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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