Myofibrillar M-line structure in normal and dystrophic hamster muscle
| Autor: | Hans M. Eppenberger, Monika E. Eppenberger, Ronnie Schoenenberger |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Physiology Hamster Fluorescent Antibody Technique Muscle Proteins Biology Immunofluorescence Cellular and Molecular Neuroscience Antigen Myofibrils Physiology (medical) Internal medicine Cricetinae medicine Animals Frozen Sections Connectin Muscular dystrophy Cells Cultured Myomesin Indirect immunofluorescence medicine.diagnostic_test Mesocricetus Muscles Myocardium Antibodies Monoclonal Muscular Dystrophy Animal medicine.disease Molecular biology Endocrinology biology.protein Neurology (clinical) Antibody Myofibril |
| Zdroj: | Musclenerve. 7(4) |
| ISSN: | 0148-639X |
| Popis: | The presence of the specific myofibrillar M-line marker, myomesin , in isolated myofibrils and cryosections of skeletal and heart muscle as well as its appearance during differentiation in skeletal and heart muscle cell cultures of normal and dystrophic hamsters were evaluated. By means of the indirect immunofluorescence technique employing antibodies against chicken M-line proteins, the appearance of antigen localized in the M-line was investigated. No difference could be found between the M-line structure of normal and dystrophic animals. The results suggest that the M-line proteins, apparently relatively stable, are not primarily affected by the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text