PR deviation as a risk marker for cardiac events in patients with Takotsubo syndrome

Autor:	Noriyoshi Yamawake, Makoto Suzuki, Masato Shimizu, Hiroyuki Fujii, Mitsuhiro Nishizaki
Rok vydání:	2018
Předmět:	Male medicine.medical_specialty 030204 cardiovascular system & hematology Electrocardiography 03 medical and health sciences 0302 clinical medicine Heart Conduction System Takotsubo Cardiomyopathy Internal medicine medicine Humans Sinus rhythm 030212 general & internal medicine PR interval Aged Killip class Ejection fraction medicine.diagnostic_test biology business.industry General Medicine medicine.disease Heart failure Ventricular fibrillation Cardiology biology.protein Female Creatine kinase Cardiology and Cardiovascular Medicine business
Zdroj:	Pacing and Clinical Electrophysiology. 41:1652-1659
ISSN:	0147-8389
DOI:	10.1111/pace.13530
Popis:	BACKGROUND PR segment deviation (PRD: defined as PR elevation in aVR and PR depression in lead II/III) on electrocardiography is frequently observed in patients with acute pericarditis; however, there have been few studies that explore the occurrence of PRD in patients with Takotsubo syndrome (TTS). The clinical significance of PRD in TTS is not clearly elucidated. METHODS & RESULTS A total of 52 consecutive patients with TTS in sinus rhythm (73.9 ± 13.8 years, nine males) were enrolled in the study. The major cardiac events were defined as sustained ventricular tachycardia or ventricular fibrillation, Killip class 4 heart failure, and cardiac death within 30 days. PRD in the hyperacute phase (within 48 h from the onset of TTS) was observed in 15 patients (29%), and all PRDs disappeared or diminished at 1 week later. The PRD (+) group had a higher value of C-reactive protein level (median: 1.80 mg/dL [0.31-3.26] vs 0.20 mg/dL [0.06-0.81], P = 0.013) and creatine kinase-muscle/brain isoenzyme (median: 60 IU/L [28-75] vs 17 IU/L [13-26], P
Databáze:	OpenAIRE
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