Prevalence of COVID-19 antibodies among operating room and critical care staff at a tertiary teaching hospital
| Autor: | Salma M Alsayed, Mansoor Radwi, Ibrahim Abushoshah, Ali Farsi, Esam I. Azhar, Sara Farsi, Wadeeah Bahaaziq, Thamir A. Alandijany, Sherif El-Kafrawy, Abdulaziz Boker |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Operating Rooms medicine.medical_specialty Infectious Disease Transmission Patient-to-Professional Critical Care Cross-sectional study Health Personnel Saudi Arabia Enzyme-Linked Immunosorbent Assay Disease 030204 cardiovascular system & hematology Antibodies Viral COVID-19 Serological Testing law.invention 03 medical and health sciences 0302 clinical medicine law Pandemic Health care Prevalence Humans Medicine Infection control 030212 general & internal medicine Hospitals Teaching Pandemics Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 business.industry COVID-19 General Medicine Odds ratio Middle Aged Antibodies Neutralizing Intensive care unit Confidence interval Cross-Sectional Studies Family medicine Female business |
| Zdroj: | Saudi Medical Journal. 42:742-749 |
| ISSN: | 1658-3175 0379-5284 |
| Popis: | OBJECTIVES: To identify the prevalence of COVID-19 antibodies among operating room and critical care staff. METHODS: In this cross-sectional study, we recruited 319 Healthcare workers employed in the operation theater and intensive care unit of King Abdulaziz University Hospital (KAUH), a tertiary teaching hospital in Jeddah, Saudi Arabia between August 9, 2020 and November 2, 2020. All participants completed a 20-item questionnaire on demographic data and COVID-19 risk factors and provided blood samples. Antibody testing was performed using an in-house enzyme immunoassay and microneutralization test. RESULTS: Of the 319 participants, 39 had detectable COVID-19 antibodies. Five of them had never experienced any symptoms suggestive of COVID-19, and only 19 were previously diagnosed with COVID-19. The odds of developing COVID-19 or having corresponding antibodies increased if participants experienced COVID-19 symptoms (odds ratio [OR], 3.1; 95% confidence interval [CI], 1.2-7.5) or reported contact with an infected family member (OR, 5.3; 95% CI, 2.5-11.2). Disease acquisition was not associated with employment in the ICU and involvement in the intubation of or close contact with COVID-19 patients. Of the 19 previously diagnosed participants, 6 did not possess any detectable COVID-19 antibodies. CONCLUSIONS: Healthcare workers may have undiagnosed COVID-19, and those previously infected may not have long-lasting immunity. Therefore, hospitals must continue to uphold strict infection control during the COVID-19 pandemic. |
| Databáze: | OpenAIRE |
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