Biologic functions of the genes responsible for familial cancer

Autor:	B. M. Boman
Rok vydání:	1994
Předmět:	Cancer Research Genes APC business.industry Cell Genes p53 Bioinformatics Malignant Growth medicine.anatomical_structure Oncology Hereditary Cancer Syndromes Neoplasms Etiology Humans Medicine Familial Cancer Genes Retinoblastoma business Gene Sporadic cancer
Zdroj:	Current Opinion in Oncology. 6:90-95
ISSN:	1040-8746
DOI:	10.1097/00001622-199401000-00013
Popis:	Clinical and molecular genetic studies on human familial cancers have provided important information toward further understanding of the etiology of hereditary and sporadic cancer. Our next challenge is to determine how mutations involving this group of genes leads to functional changes in the cell causing malignant growth. This article summarizes some of the significant findings recently reported concerning the biologic function of the genes that are involved in hereditary cancer syndromes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfa894250feeaae8173061221af6168 https://doi.org/10.1097/00001622-199401000-00013 Zobrazit plný text záznamu