Churg-Strauss syndrome presenting with focal segmental glomerulosclerosis without proteinuria: response to unconventional therapy
| Autor: | Pradipta Guha, Arindam Ray, Sanjoy Kumar Chatterjee, Indranil Thakur |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Fever Biopsy Hypereosinophilia Churg-Strauss Syndrome Kidney Focal segmental glomerulosclerosis medicine Humans Skin Proteinuria medicine.diagnostic_test Glomerulosclerosis Focal Segmental business.industry Mononeuritis Multiplex Glomerulosclerosis General Medicine medicine.disease Dermatology Treatment Outcome Kidney Diseases Radiography Thoracic medicine.symptom Vasculitis business Rare disease |
| Zdroj: | Singapore Medical Journal. 54:e13-e15 |
| ISSN: | 0037-5675 |
| DOI: | 10.11622/smedj.2013018 |
| Popis: | Churg-Strauss syndrome (CSS), or allergic granulomatosis, is a rare disease manifested by tissue infiltration, hypereosinophilia and vasculitis. Renal involvement may be seen in up to 50% of cases. We report the case of a 25-year old man who presented with a history of fever for two months, tingling, numbness, and paraesthesia of the upper limbs and left lower limb, along with diarrhoea for one month and an inability to walk for the past seven days. Serial laboratory investigations helped to reach the final diagnosis of CSS with mononeuritis multiplex, and skin, pulmonary and gastrointestinal involvement with hypertension. This is due to renal involvement in the form of focal segmental glomerulosclerosis without any nephrotic range proteinuria, which is a very rare clinical entity. The patient's symptoms were relieved after the administration of an unconventional mode of therapy. |
| Databáze: | OpenAIRE |
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