Characteristics of Hospitalized Children With SARS-CoV-2 in the New York City Metropolitan Area
| Autor: | Arun Chopra, Manno Cs, Gold-von Simson G, Asif Noor, Mona Rigaud, Adam J. Ratner, Tara M. Randis, Pradeep V. Mally, Alexandra Vinci, Colin K L Phoon, Jennifer Lighter, Benard P. Dreyer, Rishi Lumba, Heda Dapul, Rhee D, Sourabh Verma, Jonathan S. Farkas, Vanessa Raabe |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Critical Care Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medicine.medical_treatment Pediatrics Extracorporeal Cohort Studies 03 medical and health sciences 0302 clinical medicine Environmental health 030225 pediatrics medicine Humans 030212 general & internal medicine Risk factor Child Retrospective Studies Asthma Mechanical ventilation business.industry COVID-19 Infant Retrospective cohort study General Medicine medicine.disease Metropolitan area Comorbidity Obesity Hospitalization Geography Child Preschool Pediatrics Perinatology and Child Health Emergency medicine Female New York City business Cohort study |
| Zdroj: | Hospital Pediatrics. 11:71-78 |
| ISSN: | 2154-1671 2154-1663 |
| DOI: | 10.1542/hpeds.2020-001917 |
| Popis: | OBJECTIVES: To describe the characteristics of hospitalized children with severe acute respiratory syndrome coronavirus 2 in New York City metropolitan area. PATIENTS AND METHODS: This was a multicenter, retrospective cohort study at 4 hospitals comprising 82 hospitalized children (0–21 years) who tested positive for severe acute respiratory syndrome coronavirus 2 after symptoms and risk screening between March 1 and May 10, 2020. We subdivided patients on the basis of their admission to acute or critical care units and by age groups. Further subanalyses were performed between patients requiring respiratory support or no respiratory support. RESULTS: Twenty-three (28%) patients required critical care. Twenty-nine (35%) patients requiring respiratory support, with 9% needing mechanical ventilation, and 1 required extracorporeal support. All patients survived to discharge. Children with any comorbidity were more likely to require critical care (70% vs 37%, P = .008), with obesity as the most common risk factor for critical care (63% vs 28%, P = .02). Children with asthma were more likely to receive respiratory support (28% vs 8%, P = .02), with no difference in need for critical care (P = .26). Children admitted to critical care had higher rates of renal dysfunction at presentation (43% vs 10%, P = .002). CONCLUSIONS: Children with comorbidities (obesity and asthma in particular) were at increased risk for critical care admission and/or need for respiratory support. Children with renal dysfunction at presentation were more likely to require critical care. |
| Databáze: | OpenAIRE |
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