The effect of immunosuppression on protective immunity of turkey poults against infection with turkey coronavirus

Autor:	Thomas Bryan, Tsang Long Lin, Tom Hooper, Chien Chang Loa, Ching Ching Wu, Donna Schrader
Rok vydání:	2002
Předmět:	Male Turkeys T cell Immunology Turkey coronavirus Lymphocyte proliferation Antibodies Viral Lymphocyte Activation Microbiology Article Random Allocation Antigen Immunity Cyclosporin a Concanavalin A Coronavirus Turkey medicine Animals Immunology and Allergy Lymphocytes Fluorescent Antibody Technique Indirect Cyclophosphamide Antigens Viral Immunity Cellular General Veterinary biology General Medicine Virology Enteritis Intestines Cyclosporin A Infectious Diseases medicine.anatomical_structure Humoral immunity Cyclosporine biology.protein Enteritis Transmissible of Turkeys Female Antibody immunité Immunosuppression cyclosporine A Immunosuppressive Agents coronavirus des dindes
Zdroj:	Comparative Immunology, Microbiology and Infectious Diseases
ISSN:	0147-9571
DOI:	10.1016/s0147-9571(01)00033-9
Popis:	The objective of the present study was to evaluate the protective effect of humoral and cellular immunities on turkeys infected with turkey coronavirus (TCV). Two trials were conducted with two separate hatches of turkey poults. Turkeys were experimentally immunosuppressed with cyclosporin A (CsA) or cyclophosphamide (CY) and infected with TCV. Prior to infection, treatment with CsA selectively suppressed T cell activity as revealed by 2–3 fold decreased (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece940bf8d55378312c80313df0f4b0b https://doi.org/10.1016/s0147-9571(01)00033-9 Zobrazit plný text záznamu Full Text from ScienceDirect