Screening for clostridiae and treatment of clostridiae contamination to prevent fatal infections after liver transplantation
| Autor: | T Vowinkel, M Hermann, J Menzel, H.H Wolters, K.H Dietl, N Senninger, J Brockmann, D Stähle, T Vogel |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Liver transplantation Gastroenterology Sepsis Fatal Outcome Postoperative Complications Internal medicine medicine Humans Aged Clostridium Transplantation Gastrointestinal tract business.industry Incidence (epidemiology) Healthy subjects Middle Aged Contamination medicine.disease Hemolysis Liver Transplantation Surgery Clostridium Infections Female business Gas gangrene |
| Zdroj: | Transplantation Proceedings. 34:2292-2293 |
| ISSN: | 0041-1345 |
| Popis: | CLOSTRIDIAE ARE anaerobic, gram-positive, sporeforming rods, which inhabit the gastrointestinal tract of healthy subjects. With a 5.9% incidence, contamination of the bilary tract with C. perfringens is not a rare finding in patients undergoing bilary surgery. In a report of 286 isolates obtained from bile specimens 27 were identified as C. perfringens, which can cause severe infections with gas gangrene, sepsis, and hemolysis. The outcome is fatal in most cases despite surgical and antbiotic treatment, particularly for liver transplant recipients receiving immunosuppressive therapy. Survival is possible when the focus can be eliminated by early retransplantation. |
| Databáze: | OpenAIRE |
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