Laparoscopic vs. open surgery for gastrointestinal stromal tumors of esophagogastric junction: A multicenter, retrospective cohort analysis with propensity score weighting
| Autor: | Wenjun Xiong, Rui Zhou, Yong Li, Wei Wang, Yuting Xu, Jin Wan, Guoxin Li, Xingyu Feng, Tao Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Laparoscopic surgery
Cancer Research medicine.medical_specialty business.industry medicine.medical_treatment Hazard ratio Retrospective cohort study laparoscopic surgery Confidence interval gastrointestinal stromal tumor Surgery Esophagogastric junction open surgery propensity score weighting 03 medical and health sciences 0302 clinical medicine Oncology Interquartile range 030220 oncology & carcinogenesis Cohort Propensity score matching medicine Original Article business Body mass index |
| Zdroj: | Chinese Journal of Cancer Research |
| ISSN: | 1993-0631 1000-9604 |
| Popis: | Objective Laparoscopic resection is increasingly performed for gastrointestinal stromal tumors (GISTs). However, the laparoscopic approach for GISTs located in the esophagogastric junction (EGJ-GIST) is surgically challenging. This study compares the efficacy of laparoscopic surgery and the open procedure for EGJ-GIST through the propensity score weighting (PSW) method. Methods Between April 2006 and April 2018, 1,824 surgical patients were diagnosed with primary gastric GIST at four medical centers in South China. Of these patients, 228 were identified as EGJ-GISTs and retrospectively reviewed clinicopathological characteristics, operative information, and long-term outcomes. PSW was used to create the balanced cohorts. Results PSW was carried out in laparoscopic and open-surgery cohorts according to year of surgery, sex, age, body mass index (BMI), tumor size, mitotic rates and recurrence risk. After PSW, 438 patients consisting of 213 laparoscopic (L group) and 225 open surgery (O group) patients were enrolled. After PSW, the following measures in the L group were superior to those in the O group: median operative time [interquartile range (IQR)]: 100.0 (64.5-141.5)vs. 149.0 (104.0-197.5) min, P |
| Databáze: | OpenAIRE |
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