Gefarnate increases PAS positive cell density in rabbit conjunctiva
| Autor: | Ken-ichi Endo, Katsuhiko Nakata, Takashi Hamano, Masatsugu Nakamura |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Pathology
medicine.medical_specialty Gefarnate Conjunctiva Troxipide Cell Count Periodic acid–Schiff stain Cellular and Molecular Neuroscience chemistry.chemical_compound Piperidines In vivo medicine Animals Goblet cell Lagomorpha biology business.industry Mucin biology.organism_classification Anti-Ulcer Agents Sensory Systems eye diseases Ophthalmology medicine.anatomical_structure chemistry Original articles - Laboratory science Abietanes sense organs Rabbits Diterpenes Ophthalmic Solutions business |
| Zdroj: | The British journal of ophthalmology. 82(11) |
| ISSN: | 0007-1161 |
| Popis: | AIMS—The effects of three drugs for the treatment of gastritis and gastric ulcer—gefarnate, ecabet sodium, and troxipide—on periodic acid Schiff (PAS) positive cell density in rabbit conjunctiva in vivo were investigated. METHODS—Eye drops containing gefarnate (0.1%, 1%), ecabet sodium (0.1%, 1%), or troxipide (0.1%, 1%) were instilled in both eyes of rabbits, six times a day for 7 days. On the eighth day, filter paper was gently pressed on the bulbar and palpebral conjunctiva, and impression cytology was performed with PAS staining. Three points in each specimen were selected randomly, and PAS stained cells were counted. RESULTS—The instillation of gefarnate increased PAS positive cell density significantly at the concentration of 1% (p |
| Databáze: | OpenAIRE |
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