Characterization of highly multiplexed monolithic PET / gamma camera detector modules:Paper
| Autor: | Stefano Pedemonte, K. Van Leemput, Robert S. Miyaoka, Lawrence R. MacDonald, Don DeWitt, Larry Pierce, William C. J. Hunter |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Photomultiplier
Positron emission tomography Physics::Instrumentation and Detectors Detector characterizarion Detector calibration 01 natural sciences Multiplexing Signal Article Lyso 030218 nuclear medicine & medical imaging law.invention 03 medical and health sciences 0302 clinical medicine Optics law 0103 physical sciences Image Processing Computer-Assisted Calibration Humans Gamma Cameras Radiology Nuclear Medicine and imaging Gamma camera Physics Photons Scintillation Radiological and Ultrasound Technology 010308 nuclear & particles physics business.industry Detector Gamma cameras Positron-Emission Tomography Electronics business |
| Zdroj: | Pierce, L A, Pedemonte, S, Dewitt, S, Macdonald, L, Hunter, W C J, Leemput, V & Miyaoka, R 2018, ' Characterization of highly multiplexed monolithic PET / gamma camera detector modules : Paper ', Physics in Medicine and Biology, vol. 63, no. 7, 075017 . https://doi.org/10.1088/1361-6560/aab380 |
| DOI: | 10.1088/1361-6560/aab380 |
| Popis: | PET detectors use signal multiplexing to reduce the total number of electronics channels needed to cover a given area. Using measured thin-beam calibration data, we tested a principal component based multiplexing scheme for scintillation detectors. The highly-multiplexed detector signal is no longer amenable to standard calibration methodologies. In this study we report results of a prototype multiplexing circuit, and present a new method for calibrating the detector module with multiplexed data. A [Formula: see text] mm3 LYSO scintillation crystal was affixed to a position-sensitive photomultiplier tube with [Formula: see text] position-outputs and one channel that is the sum of the other 64. The 65-channel signal was multiplexed in a resistive circuit, with 65:5 or 65:7 multiplexing. A 0.9 mm beam of 511 keV photons was scanned across the face of the crystal in a 1.52 mm grid pattern in order to characterize the detector response. New methods are developed to reject scattered events and perform depth-estimation to characterize the detector response of the calibration data. Photon interaction position estimation of the testing data was performed using a Gaussian Maximum Likelihood estimator and the resolution and scatter-rejection capabilities of the detector were analyzed. We found that using a 7-channel multiplexing scheme (65:7 compression ratio) with 1.67 mm depth bins had the best performance with a beam-contour of 1.2 mm FWHM (from the 0.9 mm beam) near the center of the crystal and 1.9 mm FWHM near the edge of the crystal. The positioned events followed the expected Beer-Lambert depth distribution. The proposed calibration and positioning method exhibited a scattered photon rejection rate that was a 55% improvement over the summed signal energy-windowing method. |
| Databáze: | OpenAIRE |
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