Brain iron in progressive supranuclear palsy: clinical, magnetic resonance imaging, and neuropathological findings
| Autor: | Coffey Ce, Heinz Er, Alston S, Burger Pc |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Iron
Neurocognitive Disorders Autopsy Neuropsychological Tests Progressive supranuclear palsy Nuclear magnetic resonance medicine Humans Brain magnetic resonance imaging Gliosis FERRIC IRON Neurologic Examination Neurons Depressive Disorder medicine.diagnostic_test business.industry Brain Magnetic resonance imaging Neurofibrillary Tangles Middle Aged medicine.disease Magnetic Resonance Imaging Psychiatry and Mental health Female Neurology (clinical) Supranuclear Palsy Progressive business Tomography X-Ray Computed Deposition (chemistry) |
| Zdroj: | The Journal of neuropsychiatry and clinical neurosciences. 1(4) |
| ISSN: | 0895-0172 |
| Popis: | A patient with progressive supranuclear palsy demonstrated a region-specific decrease in T2 signal during high-field-strength brain magnetic resonance imaging. At autopsy the T2-signal hypointensity was found to correspond topographically to increased deposition of ferric iron. The potential clinical, radiologic, and pathophysiologic implications of these findings are discussed. |
| Databáze: | OpenAIRE |
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