Sex, gender and venous thromboembolism: do we care enough?
| Autor: | Nadia P Vozzo, Maddalena L. Zighetti, Elena M. Faioni |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty MEDLINE Disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Sex Factors Fibrinolytic Agents Recurrence Risk Factors Antithrombotic Epidemiology medicine Animals Humans 030212 general & internal medicine Medical prescription Intensive care medicine business.industry Confounding Hematology General Medicine Venous Thromboembolism Treatment Outcome Female Animal studies business Venous thromboembolism |
| Zdroj: | Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 29(8) |
| ISSN: | 1473-5733 |
| Popis: | The role of sex and gender in determining clinical presentation, diagnostic approach and outcomes of venous thromboembolism is not fully and systematically addressed, except for hormone-related events in women. A lack of knowledge is also apparent regarding drug prescription patterns, physician bias, enrolment in clinical studies and analysis of sex-related confounders in preclinical and clinical studies. As was shown for cardiovascular disease, ignoring sex and gender in medicine can have important impact on outcomes, including mortality. In this review, we seek to address some aspects of venous thromboembolism such as epidemiology and clinical presentation, recurrence, risk factors, animal studies, safety and efficacy of antithrombotic drugs, highlighting what is known and what is not regarding the role of sex and gender, and hoping to focus some interest and to promote the inclusion of these variables in all future studies on venous thromboembolism. |
| Databáze: | OpenAIRE |
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