日本薬学会
| Autor: | Junzo Nakamura, Nobuharu Ooe, Keiko Nagai, Mikiro Nakashima, Mihoko N. Nakashima, Koyo Nishida, Tetsuya Ueki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Constipation Adolescent medicine.medical_treatment Laxative Adverse drug reaction Pharmaceutical Science Young Adult Risk Factors Internal medicine Activities of Daily Living medicine Humans Hypnotics and Sedatives Risk factor Aged Aged 80 and over Pharmacology business.industry Case-control study Odds ratio Middle Aged Hospitalized patient medicine.disease Confidence interval Hospitalization Cerebrovascular Disorders Logistic Models Case-Control Studies Relative risk Physical therapy Female medicine.symptom business Hypnotics |
| Zdroj: | 藥學雜誌 = YAKUGAKU ZASSHI. 131(3):469-476 |
| ISSN: | 0031-6903 |
| Popis: | Constipation is a common problem in hospitalized patients; however, the relative risks of its development with various factors have not been clarified. To clarify the risk factors associated with constipation, we performed a case-controlled study of 165 hospitalized patients who were not laxative users on admission. They were divided into case (n=35) and control (n=130) groups according to laxative administration during hospitalization. Comparison of the patient backgrounds in the two groups revealed significant differences in the activities of daily living, length of fasting, rest level on admission, cerebrovascular disease, and administration of hypnotics. Multiple logistic regression analysis using these five factors as autonomous variables showed that administration of hypnotics (odds ratio, 2.79; 95% confidence interval, 1.10-7.06; p=0.031) was significantly related to laxative use. Therefore, the administration of hypnotics may be the principal cause of constipation development in hospitalized patients and they should be used with caution. 薬学雑誌, 131(3), pp.469-476; 2011 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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