Endometriosis-associated recto-sigmoid cancer: a case report

Autor: Ningning Li, Jiaolin Zhou, Weixun Zhou, Lin Zhao
Rok vydání: 2017
Předmět:
Endometriosis-associated carcinoma
Cancer Research
medicine.medical_specialty
medicine.medical_treatment
Biopsy
Endometriosis
Colonoscopy
Rectum
lcsh:RC254-282
Malignant transformation
03 medical and health sciences
0302 clinical medicine
Surgical oncology
Fluorodeoxyglucose F18
Bowel endometriosis
Positron Emission Tomography Computed Tomography
Genetics
medicine
Biomarkers
Tumor
Humans
Chemotherapy
Hysterectomy
medicine.diagnostic_test
business.industry
Cancer
Middle Aged
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
medicine.disease
Sigmoid Neoplasms
medicine.anatomical_structure
Treatment Outcome
Malignant degeneration
Oncology
Chemotherapy
Adjuvant
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Radiology
business
Tomography
X-Ray Computed
Zdroj: BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)
ISSN: 1471-2407
Popis: Background Endometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. We report a case in which a patient with a history of endometriosis underwent surgery for malignant intestinal endometriosis. Case presentation A 55-year-old woman complained of rectorrhagia and intermittent abdominal pain. A neoplasm was revealed by colonoscopy, CT scan and F18-FDG PET/CT of the recto-sigmoidal colon. The patient underwent a rectal anterior resection, hysterectomy and bilateral salpingo-oophorectomy for treatment. According to the histological and immunohistochemical presentation, the diagnosis of endometriosis-associated recto-sigmoid cancer was confirmed. The patient was treated with adjuvant chemotherapy for 6 months. During the follow-up appointment 22 months later, there was clinical and radiographic evidence of recurrence in the rectum. The patient received chemotherapy again and will receive another surgery after two more cycles of chemotherapy. Conclusion We report a case of malignant intestinal endometriosis. Although there is no standard therapy for malignant intestinal endometriosis due to the rarity of this disease, surgery and adjuvant chemotherapy seemed to be rational. This case indicates that local recurrence may be a common situation after standard therapy.
Databáze: OpenAIRE
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