Endometriosis-associated recto-sigmoid cancer: a case report
Autor: | Ningning Li, Jiaolin Zhou, Weixun Zhou, Lin Zhao |
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Rok vydání: | 2017 |
Předmět: |
Endometriosis-associated carcinoma
Cancer Research medicine.medical_specialty medicine.medical_treatment Biopsy Endometriosis Colonoscopy Rectum lcsh:RC254-282 Malignant transformation 03 medical and health sciences 0302 clinical medicine Surgical oncology Fluorodeoxyglucose F18 Bowel endometriosis Positron Emission Tomography Computed Tomography Genetics medicine Biomarkers Tumor Humans Chemotherapy Hysterectomy medicine.diagnostic_test business.industry Cancer Middle Aged lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Sigmoid Neoplasms medicine.anatomical_structure Treatment Outcome Malignant degeneration Oncology Chemotherapy Adjuvant 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female Radiology business Tomography X-Ray Computed |
Zdroj: | BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018) |
ISSN: | 1471-2407 |
Popis: | Background Endometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. We report a case in which a patient with a history of endometriosis underwent surgery for malignant intestinal endometriosis. Case presentation A 55-year-old woman complained of rectorrhagia and intermittent abdominal pain. A neoplasm was revealed by colonoscopy, CT scan and F18-FDG PET/CT of the recto-sigmoidal colon. The patient underwent a rectal anterior resection, hysterectomy and bilateral salpingo-oophorectomy for treatment. According to the histological and immunohistochemical presentation, the diagnosis of endometriosis-associated recto-sigmoid cancer was confirmed. The patient was treated with adjuvant chemotherapy for 6 months. During the follow-up appointment 22 months later, there was clinical and radiographic evidence of recurrence in the rectum. The patient received chemotherapy again and will receive another surgery after two more cycles of chemotherapy. Conclusion We report a case of malignant intestinal endometriosis. Although there is no standard therapy for malignant intestinal endometriosis due to the rarity of this disease, surgery and adjuvant chemotherapy seemed to be rational. This case indicates that local recurrence may be a common situation after standard therapy. |
Databáze: | OpenAIRE |
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