Quantitative determination of the cholinesterase inhibitor physostigmine in brain tissue samples using reversed-phase high-performance liquid chromatography
| Autor: | D. J. De Wildt, H.H. van Rooy, A. J. Porsius |
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| Rok vydání: | 1981 |
| Předmět: |
Detection limit
Brain Chemistry Male Physostigmine Chromatography biology Chemistry Extraction (chemistry) Brain General Chemistry Brain tissue High-performance liquid chromatography Quantitative determination Phase (matter) Injections Intravenous biology.protein medicine Cats Animals Female Cholinesterase Inhibitors Chromatography High Pressure Liquid Cholinesterase medicine.drug |
| Zdroj: | Journal of chromatography. 225(2) |
| Popis: | A high-performance liquid chromatographic method, based on a dynamic cation-exchange system was used for the determination of physostigmine in brain tissue extracts. The precision and detection limit of the method as well as the extraction efficiency were established. The distribution of physostigmine over several parts of the brain after intravertebral application is reported. |
| Databáze: | OpenAIRE |
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