Calcium metabolism in a fatal case of sodium fluoride poisoning
| Autor: | Richard M Evans, Elliott Simpson, LG Shankara Rao, J Christine Rodger, Anil Lakhani, William Wilkie |
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| Rok vydání: | 1980 |
| Předmět: |
Calcium metabolism
Male 030213 general clinical medicine Chemistry Clinical Biochemistry 030209 endocrinology & metabolism General Medicine Pharmacology Middle Aged 03 medical and health sciences chemistry.chemical_compound Fluorides 0302 clinical medicine Biochemistry Apatites Sodium fluoride Humans Sodium Fluoride Calcium Magnesium General hospital Fluoride Poisoning |
| Zdroj: | Annals of clinical biochemistry. 17(1) |
| ISSN: | 0004-5632 |
| Popis: | A patient was admitted to a district general hospital within an hour of ingesting a fatal dose of sodium fluoride. The results of laboratory investigations, together with some in vitro findings, support the hypothesis that the hypocalcaemia of fluoride poisoning is the result of fluorapatite formation and not calcium fluoride precipitation, and that its persistence reflects the severity of the calcium deficit and not an inhibition of normal homeostatic mechanisms. It is suggested that the role of renal clearance of fluoride may be more important than had been realised hitherto. |
| Databáze: | OpenAIRE |
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