Analytical methods for copper, zinc and iron quantification in mammalian cells

Autor:	Tania Maria Manieri, Fernanda R. Bertuchi, Giselle Cerchiaro
Rok vydání:	2013
Předmět:	Mammals Detection limit Chemistry Cells Iron Metals and Alloys Biophysics chemistry.chemical_element Nanotechnology Zinc Biochemistry Copper Chemistry Techniques Analytical Biomaterials Chemistry (miscellaneous) Animals Humans Biochemical engineering Literature survey
Zdroj:	Metallomics. 5:1336
ISSN:	1756-591X 1756-5901
DOI:	10.1039/c3mt00136a
Popis:	Highly complex analytical methods with different accuracies of measurement, reproducibilities and ease of analyses are currently being used to quantify metals in cellular media and tissue samples. In this review, the analytical methods commonly used for iron, copper and zinc quantification in mammalian cells are presented and discussed. Herein, we present a literature survey of the most commonly found concentrations of these metals in various mammalian cells in culture and tissues. The aim of this review is to help researchers in metallomic-related areas identify the method that best suits their needs for the accurate quantification of these metals in cells. This accuracy goes beyond simple knowledge of the limit of detection of each technique and needs to be evaluated through comparisons with similar previous studies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb55574a618ce964ed5ede026840384 https://doi.org/10.1039/c3mt00136a Zobrazit plný text záznamu