A nation-wide retrospective epidemiological study of gastroenteropancreatic neuroendocrine neoplasms in china
| Autor: | Yuan-Jia Chen, Qing Liu, Li Ma, Xing-Hua Yuan, Li-Ming Jiang, Susheng Shi, Xibin Sun, Yihebali Chi, Katrina Deloso, Yutong He, You-Lin Qiao, Yu-Qing Zhang, Shaoming Wang, Jin-Hu Fan, Chang-Yan Feng |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Veterinary medicine Referral 03 medical and health sciences 0302 clinical medicine digestive system Epidemiology Epidemiology of cancer Medicine retrospective study multicenter study China Cancer prevention business.industry Cancer Retrospective cohort study medicine.disease Cancer registry 030104 developmental biology Oncology 030220 oncology & carcinogenesis Family medicine epidemiology neuroendocrine tumors business Research Paper |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| Popis: | // Jin-Hu Fan 1, * , Yu-Qing Zhang 1, * , Su-Sheng Shi 2 , Yuan-Jia Chen 3 , Xing-Hua Yuan 4 , Li-Ming Jiang 5 , Shao-Ming Wang 1 , Li Ma 6 , Yu-Tong He 7 , Chang-Yan Feng 8 , Xi-Bin Sun 9 , Qing Liu 10 , Katrina Deloso 11 , Yihebali Chi 12 and You-Lin Qiao 1 1 Department of Cancer Epidemiology, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College 2 Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College 3 Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences 4 Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College 5 Department of Radiology, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College 6 Department of Epidemiology, Dalian Medical University 7 Hebei Cancer Registry, the Fourth hospital of Hebei medical university 8 Department of Nutrition, Chongqing Cancer Hospital & Institute & Cancer Center 9 Department of Cancer Epidemiology, Henan Cancer Hospital/Institute 10 Department of Cancer Prevention, Sun Yat-sen University Cancer Center 11 Division of Biological Sciences, the University of Chicago 12 Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College * These authors have contributed equally to this work Correspondence to: You-Lin Qiao, email: Qiaoy@cicams.ac.cn Yihebali Chi, email: yihebalichi@hotmail.com Keywords: neuroendocrine tumors, digestive system, epidemiology, retrospective study multicenter study Received: October 20, 2016 Accepted: April 11, 2017 Published: May 03, 2017 ABSTRACT Background: Representative data on the gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) in Asian patients is rare, especially in China. This study aims to create a GEP-NENs profile of Chinese patients. Methods: This was a hospital-based, nation-wide, and multi-center 10-year (2001-2010) retrospective study which collected GEP-NEN patients’ information in tertiary referral hospitals. All 2010 inpatient GEP-NEN cases with confirmed pathology in the selected hospitals were included. The primary GEP-NEN sites were measured and the epidemiological and clinical information of each tumor site were compared. Results: The most common primary sites for GEP-NEN were the pancreas (31.5%) and rectum (29.6%), followed by the cardia (11.6%) and body (15.4%) of stomach. Small intestinal and colonic NENs took up a relatively small proportion of all patients. Pancreatic and rectal NENs, rather than cardiac and gastric body NENs, tended to be found in younger ( P |
| Databáze: | OpenAIRE |
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