A randomized controlled TRIal of cognitive BEhavioral therapy for high Catastrophizing in patients undergoing lumbar fusion surgery: the TRIBECA study

Autor: Anouk Y.J.M. Smeets, Madelon L. Peters, P. Scarone, H. van Santbrink, Eva Koetsier, S. M. J. van Kuijk
Přispěvatelé: MUMC+: MA AIOS Neurochirurgie (9), RS: MHeNs - R3 - Neuroscience, Neurochirurgie, MUMC+: KIO Kemta (9), Epidemiologie, RS: CAPHRI - R2 - Creating Value-Based Health Care, MUMC+: MA Med Staf Spec Neurochirurgie (9), Section Experimental Health Psychology, RS: FPN CPS I
Jazyk: angličtina
Rok vydání: 2020
Předmět:
lcsh:Diseases of the musculoskeletal system
medicine.medical_treatment
law.invention
Study Protocol
0302 clinical medicine
Randomized controlled trial
law
Chronic postsurgical pain (CPSP)
Orthopedics and Sports Medicine
Single-Blind Method
030212 general & internal medicine
Prospective Studies
CHRONIC POSTSURGICAL PAIN
PREDICTORS
Pain catastrophizing
SPONDYLOLISTHESIS
education.field_of_study
COMPLICATIONS
Rehabilitation
Lumbar Vertebrae
Catastrophization
Chronic pain
DEPRESSION
Cognitive behavioral therapy
Treatment Outcome
LOW-BACK-PAIN
REHABILITATION
Adult
medicine.medical_specialty
Population
Pedicle screws
Education
03 medical and health sciences
Lumbar
Rheumatology
medicine
MANAGEMENT
Humans
education
Cognitive behavioral therapy (CBT)
Cognitive Behavioral Therapy
business.industry
Perioperative
OUTCOME MEASURES
medicine.disease
Lumbar spinal fusion surgery
INDIVIDUALS
Spinal Fusion
Physical therapy
Quality of Life
lcsh:RC925-935
business
030217 neurology & neurosurgery
Zdroj: BMC Musculoskeletal Disorders, Vol 21, Iss 1, Pp 1-12 (2020)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, 21(1):810. BioMed Central Ltd
ISSN: 1471-2474
Popis: Background Around 20% of patients undergoing spinal fusion surgery have persistent back or leg pain despite surgery. Pain catastrophizing is the strongest psychological predictor for chronic postsurgical pain. Psychological variables are modifiable and could be target for intervention. However, randomized controlled trials evaluating the effectiveness of psychological interventions to reduce chronic pain and disability after spinal fusion in a population of patients with high preoperative pain catastrophizing scores are missing. The aim of our study is to examine whether an intervention targeting pain catastrophizing mitigates the risk of chronic postsurgical pain and disability. Our primary hypothesis is that targeted perioperative cognitive behavioral therapy decreases the risk of chronic postsurgical pain and disability after spinal fusion surgery in high catastrophizing patients. Methods We will perform a two-center prospective, single-blind, randomized, controlled study comparing lumbar spinal fusion surgery outcome between 2 cohorts. Adult patients selected for lumbar spinal fusion with decompression surgery and a minimum score of 24 on the pain catastrophizing scale will be randomized with 1:1 allocation for either perioperative cognitive behavioral therapy (intervention group) or a perioperative education plus progressive exercise program (control group). Patients randomized to the intervention group will receive six individual sessions of cognitive behavioral therapy, two sessions before the operation and four after. Primary outcome is the Core Outcome Measures Index at 12 months. Secondary outcomes include pain, disability, depression and quality of life. Discussion This is the first trial that evaluates the effectiveness of cognitive behavioral therapy as a perioperative tool to improve pain and disability after spinal fusion surgery in comparison with an educational/exercise control intervention, in patients with high levels of pain catastrophizing. If perioperative cognitive behavioral therapy proves to be effective, this might have important clinical implications, reducing the incidence of chronic postsurgical pain and improving outcome after spinal fusion surgery. Trial registration Clinicaltrials (NCT03969602). Registered 31 May 2019
Databáze: OpenAIRE
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