Lipo- and apolipoproteins in a population survey subset in MONICA-Israel
Autor: | D. Brunner, R. Lingel, S. Schwartz, J. Weisbort, G.M. Slutzky |
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Rok vydání: | 1988 |
Předmět: |
Adult
Male medicine.medical_specialty Apolipoprotein B Lipoproteins chemistry.chemical_compound Age groups Nephelometry and Turbidimetry Internal medicine Internal Medicine medicine Humans Israel Apolipoproteins A Population survey Apolipoproteins B Baseline values Ldl cholesterol biology Cholesterol business.industry Cholesterol HDL Middle Aged Endocrinology Apolipoproteins chemistry Coronary risk Population Surveillance biology.protein Population study lipids (amino acids peptides and proteins) Female business |
Zdroj: | Acta medica Scandinavica. Supplementum. 728 |
ISSN: | 0365-463X |
Popis: | Lipo- and apolipoproteins in a population survey subset in MONICA-Israel. A group of 169 healthy men and women selected at random from the population survey of the MONICA-Israel Project were screened for baseline values of serum lipoproteins and apolipoprotein A-I and B concentrations. The apolipoprotein measurements were obtained using a recently developed immunoturbidimetric assay. The study population was subdivided into age groups of 25–44 years and 45–64 years. It was found that women aged 45–64 years had significantly higher levels of apolipoprotein A-I, apolipoprotein B, total cholesterol (TC), LDL cholesterol (LDL-c) and a lower ratio of HDL-cholesterol (HDL-c) to TC (HDL-c%) than did their younger counterparts. These parameters did not differ significantly between younger and older men. The results suggest that the HDL of women over the age of 45 years contains relatively less cholesterol and more protein than the HDL of younger women. Further studies will show to what degree apolipoprotein concentrations, and their relation to lipoproteins will sharpen the assessment of coronary risk. |
Databáze: | OpenAIRE |
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