Primary intraocular lymphoma arising during methotrexate treatment of temporal arteritis
| Autor: | David Tingey, Alain A. Proulx, J. Godfrey Heathcote, Sylvia Rodrigues, Kamilia Rizkalla |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphoma B-Cell Retinal Neoplasm genetic structures Biopsy Retinal Neoplasms Giant Cell Arteritis Eye Enucleation Prednisone Biomarkers Tumor medicine Humans Arteritis Aged 80 and over business.industry General Medicine medicine.disease Immunohistochemistry eye diseases Lymphoma Ophthalmology Giant cell arteritis Methotrexate Central retinal artery occlusion Female sense organs Intraocular lymphoma business Immunosuppressive Agents medicine.drug |
| Zdroj: | Canadian Journal of Ophthalmology. 40:585-592 |
| ISSN: | 0008-4182 |
| Popis: | Case report: Primary intraocular lymphoma arose over a period of 9 months in the left eye of an 81-year-old woman who was blind in both eyes from temporal arteritis. During this period, she was treated with prednisone and methotrexate. Following a sudden total hyphema, the eye was enucleated. Examination revealed that, in addition to iris neovascularisation and central retinal artery occlusion, the neurosensory retina was replaced by atypical lymphocytes. Comments: Histological and immunohistochemical studies confirmed the presence of a lymphoma with features indicative of an immunosuppression-related disorder. The relationship of the lymphoma to the vascular changes within the eye is discussed. |
| Databáze: | OpenAIRE |
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