Establishment of new complete blood count reference values for healthy Thai adults
| Autor: | O. Komkhum, Somsak Laiwejpithaya, B. Thaowto, B. Wesarachkitti, N. Chuangsuwanich, Preechaya Wongkrajang, C. Mokkhamakkun, Wimol Chinswangwatanakul |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Anemia Lymphocyte Clinical Biochemistry Ethnic origin 030204 cardiovascular system & hematology Hematocrit Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Reference Values Internal medicine Humans Medicine Medical history Mean corpuscular hemoglobin concentration medicine.diagnostic_test Clinical pathology business.industry Biochemistry (medical) Complete blood count Hematology General Medicine Middle Aged Thailand medicine.disease Healthy Volunteers Blood Cell Count medicine.anatomical_structure 030220 oncology & carcinogenesis Female business |
| Zdroj: | International Journal of Laboratory Hematology. 40:478-483 |
| ISSN: | 1751-5521 |
| DOI: | 10.1111/ijlh.12843 |
| Popis: | Introduction Laboratory reference ranges are essential for diagnostic orientation and treatment decision. As complete blood count parameters are influenced by various factors, including gender, geographic origin, and ethnic origin, it is important to establish specific hematologic reference values for specific populations. Methods This study was conducted at the Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Blood samples were taken from healthy adults aged 18-60 years that attended a health check-up program at our hospital during February 2015 to July 2015. Hematologic and routine chemistry analysis were performed. Participants were determined to be healthy based on medical history and routine medical examinations. Serum vitamin B12, folate, ferritin, and hemoglobin typing were also analyzed to exclude the possible presence of anemia. Results A statistically significant difference was observed between males and females for Hb level, hematocrit level, red blood cell count, mean corpuscular hemoglobin concentration, percentage neutrophils, monocytes and eosinophils, and absolute neutrophil, lymphocyte, basophil, and platelet counts. Accordingly, gender-specific reference intervals were established for all complete blood count parameters in healthy Thai adult population. Conclusions The reference value ranges established in this study reflect significant differences between genders. It is possible that these reference ranges may be generalizable to adults living in Thailand. The findings of this study emphasize the importance of establishing specific hematologic reference values for specific populations. |
| Databáze: | OpenAIRE |
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