Effect of iron deficiency anemia on the development of atherosclerosis in chicks
| Autor: | Mofakhkharul Bari, M. Ataur Rahman |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Anemia Arteriosclerosis Biology Fatty Acids Nonesterified chemistry.chemical_compound Basal (phylogenetics) Hemoglobins hemic and lymphatic diseases Internal medicine Aortic tissue medicine Animals Aorta Phospholipids Triglycerides Anemia Hypochromic Cholesterol Iron deficiency medicine.disease Endocrinology chemistry Iron-deficiency anemia Hematocrit Lipid content Hemoglobin Cardiology and Cardiovascular Medicine Chickens |
| Zdroj: | Atherosclerosis. 21(3) |
| ISSN: | 0021-9150 |
| Popis: | The effect of iron deficiency anemia on the development of atherosclerosis was investigated in chicks. The control group of birds were fed a basal diet, the atherosclerosis group received 1 % cholesterol, while the atherosclerosis-anemia group were given an iron-deficient diet containing 1 % cholesterol. The lipid content of the aortas of the chicks in atherosclerosis and atherosclerosis-anemia groups was much greater as compared with the control group; the birds in the atherosclerosis-anemia group also developed anemia of appreciable severity in 12 weeks. Hemoglobin and PCV were taken as the index of anemia, while the lipid constituents were determined in plasma and aortic tissue for atherosclerosis. Hypercholesterolemia of almost equal severity occurred in both atherosclerosis and atherosclerosis-anemia groups. The abnormal rise of cholesterol and other lipid material in the aortas of the atherosclerosis and atherosclerosis-anemia groups of birds indicates that iron deficiency anemia did not markedly affect the development of atherosclerosis; it did not offer any protection in chickens and, in fact, a slight potentiating effect was observed. |
| Databáze: | OpenAIRE |
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