A novel fully tapered, self-cutting tissue-level implant: non-inferiority study in minipigs

Autor: Wayne Kye, Aikaterini Georgantza, Benjamin Bellón, Itai Sabbag, Algirdas Puisys, Benjamin E. Pippenger, Edgard El Chaar
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical Oral Investigations
El Chaar, Edgard; Puisys, Algirdas; Sabbag, Itai; Bellón, Benjamin; Georgantza, Aikaterini; Kye, Wayne; Pippenger, Benjamin E. (2021). A novel fully tapered, self-cutting tissue-level implant: non-inferiority study in minipigs. Clinical oral investigations, 25(11), pp. 6127-6137. Springer 10.1007/s00784-021-03912-w
ISSN: 1436-3771
1432-6981
DOI: 10.1007/s00784-021-03912-w
Popis: Objectives To assess the osseointegration and crestal bone level maintenance of a novel fully tapered self-cutting tissue-level implant for immediate placement (test) compared to a clinically established tissue-level implant (control) in moderate bone quality. Materials and methods Test and control implants were compared in 3 groups, i.e., small-, medium-, and large-diameter implants in an edentulous mandibular minipig model with moderate bone quality after 12 weeks of healing. Histometrically derived bone-to-implant contact (BIC) and first bone-to-implant contact (fBIC) were subjected to statistical non-inferiority testing. Maximum insertion torque values in artificial bone were assessed for comparison. Results BIC values for the tests and control implants for all 3 diameters were comparable and non-inferior: small diameter (61.30 ± 10.63% vs. 54.46 ± 18.31%) (p=0.99), medium diameter (60.91 ± 14.42 vs. 54.68 ± 9.16) (p=0.55), and large diameter (45.60 ± 14.67 vs. 52.52 ± 14.76) (p=0.31). fBIC values for test implants were higher and non-inferior compared to control implants in all three groups. Test implants further showed distinctly higher maximum insertion torque values compared to control implants. Conclusion The investigated novel tissue-level implant is able to achieve high levels of primary and secondary implant stability under simultaneous preservation of crestal bone levels. This qualifies the studied implant as an attractive candidate for immediate placement in bone of limited quality. Clinical relevance This pilot pre-clinical study investigated a novel tissue-level implant for immediate placement. With the aim of translating the studied prototype into clinical application pre-clinical models, procedures and controls have been chosen with the aim of reflecting its future clinical indication and use.
Databáze: OpenAIRE
Externí odkaz: