Glycoprotein expression in mouse cerebellum: Effects of inhibitors of vesicle function
| Autor: | Mark Carroll, Margaret M. Bird |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Cerebellum Glycoside Hydrolases Gene Expression Golgi Apparatus Cyclopentanes Biology Biochemistry Mice chemistry.chemical_compound Organ Culture Techniques Ammonia medicine Animals Diethylcarbamazine Monensin Glycoproteins chemistry.chemical_classification Brefeldin A Vesicle Embryo Mammalian In vitro medicine.anatomical_structure Enzyme chemistry Cell culture Glycoprotein |
| Zdroj: | International Journal of Biochemistry. 23:1293-1299 |
| ISSN: | 0020-711X |
| DOI: | 10.1016/0020-711x(91)90230-k |
| Popis: | 1. 1. Explants of cerebellum from foetal mouse were cultured in vitro for 10 days in the presence of one of 5 inhibitors of vesicle function (ammonia, brefeldin A, carbonyl cyanide m-chlorophenylhydrazone, diethylcarbamazine, and monensin). 2. 2. The effects of the inhibitors were compared with respect to: (a) the activity of enzymes involved in glycoprotein biosynthesis and degradation; (b) the expression of N-linked glycoproteins; (c) the morphology and ultrastructue of the cerebellar explants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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