| Autor: |
Thomas Kroker, Miroslaw Wyczesany, Maimu Alissa Rehbein, Kati Roesmann, Ida Wessing, Markus Junghöfer |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports. 12 |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-24526-6 |
| Popis: |
SummaryThe framing-effect is a bias that affects decision-making depending on whether the available options are presented with positive or negative connotations. Even when the outcome of two choices is equivalent, people have a strong tendency to avoid the negatively framed option because losses are perceived about twice as salient as gains of the same amount (i.e. loss-aversion). The ventromedial prefrontal cortex (vmPFC) is crucial for rational decision-making, and dysfunctions in this region have been linked to cognitive biases, impulsive behavior and gambling addiction. Using a financial decision-making task in combination with magnetoencephalographic neuroimaging, we show that excitatory compared to inhibitory non-invasive transcranial direct current stimulation (tDCS) of the vmPFC reduces framing-effects while improving the assessment of loss-probabilities, ultimately leading to increased overall gains. Behavioral and neural data consistently suggest that this improvement in rational decision-making is predominately a consequence of reduced loss-aversion. These findings recommend further research towards clinical applications of vmPFC-tDCS in addictive disorders. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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