Radiation-Induced Uterine Carcinosarcoma after Concurrent Chemoradiotherapy for Cervical Squamous Cell Carcinoma
| Autor: | Tsung-Hsun Tsai, Joana Moreira-Barros, Kuan-Gen Huang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Neoplasms Radiation-Induced cervical cancer Uterine Cervical Neoplasms carcinosarcoma 03 medical and health sciences Fatal Outcome 0302 clinical medicine Carcinosarcoma medicine Carcinoma Humans Cervical canal Uterine Neoplasm Cervix radiation-induced neoplasms Cervical cancer 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Stage IIB Cervical Cancer Chemoradiotherapy Gynecology and obstetrics Middle Aged medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis Carcinoma Squamous Cell RG1-991 Female Radiology uterine neoplasms business carcinogenesis |
| Zdroj: | Revista Brasileira de Ginecologia e Obstetrícia, Vol 40, Iss 12, Pp 800-802 (2018) |
| ISSN: | 1806-9339 0100-7203 |
| DOI: | 10.1055/s-0038-1673678 |
| Popis: | Objective To describe a case of radiation-induced uterine carcinosarcoma 6 years after a cervical squamous cell carcinoma treatment, which imposed some diagnostic and management challenges. Case Report A 57-year-old woman with a history of pelvic chemoradiotherapy ∼ 6.5 years before the event described in this study, following an International Federation of Gynecology and Obstetrics (FIGO) stage IIB cervical cancer, presented with a cervical mass, involving the uterine cavity, the cervical canal and the upper two thirds of the vagina. The biopsy showed a poorly differentiated carcinoma, and a positron emission tomography (PET) scan excluded distant metastasis, although it was unable to define the origin of the tumor as either a new primary malignancy of the endometrium/cervix or as a cervical recurrence. Surgical staging procedure was performed, and the diagnosis was endometrial carcinosarcoma, FIGO stage IIB. The patient was not able to complete the adjuvant therapy, and the progression of the disease was remarkable. Conclusion The present case highlights one of the less common but more serious consequences of radiotherapy for cervical cancer, which has an increasing incidence in younger women, raising concerns about the long-term consequences of its management. |
| Databáze: | OpenAIRE |
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