The effects of menthol isomers on nasal sensation of airflow
| Autor: | Neil Tolley, Ronald Eccles, D. H. Griffiths, C. G. Newton |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Adolescent Chemical Phenomena Sensory Receptor Cells Airflow Sensation chemistry.chemical_compound otorhinolaryngologic diseases Humans Medicine Nasal resistance Inhalation business.industry Airway Resistance Stereoisomerism respiratory system Sensory Nerve Endings respiratory tract diseases Pharmacological action Chemistry Menthol Otorhinolaryngology chemistry Anesthesia Female business |
| Zdroj: | Clinical Otolaryngology. 13:25-29 |
| ISSN: | 1749-4486 1749-4478 |
| DOI: | 10.1111/j.1365-2273.1988.tb00277.x |
| Popis: | The effects of inhalation of L-menthol, D-isomenthol and D-neomenthol, upon nasal resistance and sensation to airflow were investigated in 40 subjects. L-menthol caused a highly significant enhancement of nasal sensation of airflow but despite their great similarity in structure and a similar peppermint smell the isomers D-isomenthol and D-neomenthol had no effect on nasal sensation of airflow. These findings show that L-menthol has a specific pharmacological action on nasal sensory nerve endings which is not related to its peppermint smell. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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