Prenatal androgen exposure and children’s aggressive behavior and activity level
Autor: | Vivette Glover, Sharon Neufeld, Thomas G. O'Connor, Vickie Pasterski, Carlo L. Acerini, Melissa Hines, Ieuan A. Hughes, Peter C. Hindmarsh, Debra Spencer |
---|---|
Přispěvatelé: | Spencer, Debra [0000-0003-0098-5658], Neufeld, Sharon [0000-0001-5470-3770], Acerini, Carlo [0000-0003-2121-5871], Apollo - University of Cambridge Repository |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Activity level Male medicine.medical_specialty Amniotic fluid medicine.drug_class Poison control Motor Activity Article 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Endocrinology Child Development prenatal testosterone exposure Pregnancy Internal medicine medicine Humans congenital adrenal hyperplasia Congenital adrenal hyperplasia Testosterone Child Exercise Sex Characteristics Adrenal Hyperplasia Congenital Endocrine and Autonomic Systems Aggression aggression activity level Androgen medicine.disease Amniotic Fluid amniotic fluid testosterone 030104 developmental biology Case-Control Studies Child Preschool Prenatal Exposure Delayed Effects Androgens Female medicine.symptom Psychology 030217 neurology & neurosurgery Sex characteristics |
Popis: | Some human behaviors, including aggression and activity level, differ on average for males and females. Here we report findings from two studies investigating possible relations between prenatal androgen and children’s aggression and activity level. For study 1, aggression and activity level scores for 43 girls and 38 boys, aged 4 to 11 years, with congenital adrenal hyperplasia (CAH, a genetic condition causing increased adrenal androgen production beginning prenatally) were compared to those of similarly-aged, unaffected relatives (41 girls, 31 boys). Girls with CAH scored higher on aggression than unaffected girls, d = 0.69, and unaffected boys scored higher on activity level than unaffected girls, d = 0.50. No other group differences were significant. For study 2, the relationship of amniotic fluid testosterone to aggression and activity level was investigated in typically-developing children (48 girls, 44 boys), aged 3 to 5 years. Boys scored higher than girls on aggression, d = 0.41, and activity level, d = 0.50. However, amniotic fluid testosterone was not a significant predictor of aggression or activity level for either sex. The results of the two studies provide some support for an influence of prenatal androgen exposure on children’s aggressive behavior, but not activity level. The within-sex variation in amniotic fluid testosterone may not be sufficient to allow reliable assessment of relations to aggression or activity level. |
Databáze: | OpenAIRE |
Externí odkaz: |