Infections developing in patients undergoing livertransplantation: Recipients of living donors may be moreprone to bacterial/fungal infections

Autor: Sezgin Ulukaya, Fulya Gunsar, Deniz Nart, Nuri Deniz, A. Uguz, Funda Ozgenc, Funda Yilmaz, Cansu Bulut Avşar, Ilker Turan, Tansu Yamazhan, Kutsal Turhan, Ömer Ünalp, Ezgi Guler, Aysin Zeytinoglu, Zeki Karasu, Orkan Ergün, Şöhret Aydemir, Meltem Taşbakan, Rüçhan Sertöz, Murat Zeytunlu
Přispěvatelé: Ege Üniversitesi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
medicine.medical_treatment
education
Liver transplantation
Primary disease
Severity of Illness Index
End Stage Liver Disease
03 medical and health sciences
Liver disease
Young Adult
0302 clinical medicine
Postoperative Complications
Risk Factors
Internal medicine
Living Donors
Medicine
Humans
In patient
living donor liver transplantation
health care economics and organizations
Aged
Retrospective Studies
Immunosuppression Therapy
business.industry
post-transplant infection
Original Article: Liver
Gastroenterology
Diabetes status
Immunosuppression
Bacterial Infections
Middle Aged
medicine.disease
Liver Transplantation
Transplantation
Parenteral nutrition
Liver
Mycoses
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
business
Zdroj: Turk J Gastroenterol
Popis: Background/Aims: Despite surgical advances in liver transplantation and effective prophylactic strategies, posttransplant infections are the most important cause of morbidity and mortality. Diagnosis and management of infections because of developing immunosuppression is difficult and adversely affects mortality. This study aimed to review bacterial and fungal infections in patients after liver transplantation and to reveal the resistance rates. Materials and Methods: A total of 107 patients who underwent liver transplantation between January 2017 and February 2018 were evaluated retrospectively with regard to demographic characteristics, causes of transplantation, conditions that may lead to infection, postoperative infections, pathogens, and resistance patterns. Results: of the 107 patients who underwent liver transplantation, 48 (44.8%) had an infection. Bacterial infections were detected in 41% of the patients, and fungal infections were found in 13%. When we compared living and cadaveric transplants in terms of infection development, these rates were found to be 53% and 33%, respectively (p=0.034). No statistically significant results could be obtained when evaluating conditions such as sex, presence of underlying primary disease, Model for End-Stage Liver Disease MELD score, diabetes status, total parenteral nutrition, and risk factors for infection. Conclusion: After liver transplantation, infections are often seen in the first month of the postoperative period. Knowing the most common pathogens and resistance states in this process reduces infection-related deaths by providing appropriate treatment regimens at the right time.
Infect Dis & Clin Microbiol Special Soc Turkey
Databáze: OpenAIRE
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